Downregulation of lipin-1 induces insulin resistance by increasing intracellular ceramide accumulation in C2C12 myotubes
Nutrients | Free Full-Text | Lipid-Induced Insulin Resistance in Skeletal Muscle: The Chase for the Culprit Goes from Total Intramuscular Fat to Lipid Intermediates, and Finally to Species of Lipid Intermediates
Long-chain ceramides are cell non-autonomous signals linking lipotoxicity to endoplasmic reticulum stress in skeletal muscle | Nature Communications
The integrative biology of type 2 diabetes | Nature
AdipoR agonist increases insulin sensitivity and exercise endurance in AdipoR-humanized mice | Communications Biology
Long-chain ceramides are cell non-autonomous signals linking lipotoxicity to endoplasmic reticulum stress in skeletal muscle | Nature Communications
Frontiers | The Role of Ceramides in Diabetes and Cardiovascular Disease Regulation of Ceramides by Adipokines
Nutrients | Free Full-Text | Sulforaphane Prevents Hepatic Insulin Resistance by Blocking Serine Palmitoyltransferase 3-Mediated Ceramide Biosynthesis
Ceramides are early responders in metabolic syndrome development in rhesus monkeys | Scientific Reports
Ceramides are early responders in metabolic syndrome development in rhesus monkeys | Scientific Reports
Beta-cell specific Insr deletion promotes insulin hypersecretion and improves glucose tolerance prior to global insulin resistance | Nature Communications
Long-chain ceramides are cell non-autonomous signals linking lipotoxicity to endoplasmic reticulum stress in skeletal muscle | Nature Communications
Long-chain ceramides are cell non-autonomous signals linking lipotoxicity to endoplasmic reticulum stress in skeletal muscle | Nature Communications
Plasma sphingolipids are biomarkers of metabolic syndrome in non-human primates maintained on a Western-style diet | International Journal of Obesity
Frontiers | Ceramides in Adipose Tissue
Sphingolipids produced by gut bacteria enter host metabolic pathways impacting ceramide levels | Nature Communications
IJMS | Free Full-Text | Ceramides as Mediators of Oxidative Stress and Inflammation in Cardiometabolic Disease
Distinct mechanisms involving diacylglycerol, ceramides, and inflammation underlie insulin resistance in oxidative and glycolytic muscles from high fat-fed rats | Scientific Reports
Long-chain ceramides are cell non-autonomous signals linking lipotoxicity to endoplasmic reticulum stress in skeletal muscle | Nature Communications
A selective inhibitor of ceramide synthase 1 reveals a novel role in fat metabolism | Nature Communications
Metabolic Messengers: ceramides | Nature Metabolism
